3.How Emerging Therapies Are Turning the Corner in the Post-Epidemic Era?Taiwan Energy...Cellular therapy or gene therapy

Breakthroughs, conquests and cures are the human gestures to face diseases and challenge the survival of life. Behind the development of each emerging medical technology and treatment lies the accumulation of major scientific discoveries and technological inventions of human beings, and all the research and development of medicines can be said to be a history of 30-40 years of development of medical science.

Taking the m RNA technology platform of COVID-19 vaccine as an example, Hungarian scientist Katalin Kariko also went through a lot of painstaking efforts and persistence on m RNA technology for 30 years, and it was only in the COVID-19 pandemic challenge that he became a success, resulting in the story of BNT and Moderna in the emergence of m RNA vaccine technology.

Currently, there are many types of emerging technology therapies, which can broadly include regenerative medicine therapies, cell & gene therapy (CGT), immuno-oncology (IO), bispecific antibody (BsAb), CAR-T cell therapy (chimeric antigen receptor- T-cell, CAR-T), antibody drug conjugate (ADC), CRISPR/Case9, and CRISPR/Case9 gene therapy (CRISPR/Case9), and antibody drug conjugate (CRISPR/Case9, ADC). antigen receptor- T-cell (CAR-T), antibody drug conjugate (ADC), CRISPR/Case9 gene editing, nucleic acid drugs (antisense oligonucleotide (ASO), small interfering RNA (siRNA), and other drugs. (ASO), small interfering RNA (siRNA), nucleic acid aptamers (RNA aptamer), and messenger RNA (mRNA)), or exosomes (exosome). As of early 2022, the USFDA has approved more than 20 quasi-cell and gene therapies, 7 CAR-T cell therapies, 4 bispecific antibodies, 13 antibody-drug complexes, and 13 nucleic acid drugs.