{"id":8084,"date":"2026-06-29T10:21:32","date_gmt":"2026-06-29T02:21:32","guid":{"rendered":"https:\/\/witology.com.tw\/daily-biohealth\/2026-06-29\/"},"modified":"2026-06-29T10:21:32","modified_gmt":"2026-06-29T02:21:32","slug":"9-83","status":"publish","type":"page","link":"https:\/\/witology.com.tw\/en\/daily-biohealth\/9-83\/","title":{"rendered":"\u751f\u91ab\u5927\u5065\u5eb7\u7522\u696d\u65e5\u5831 2026-06-29\uff5cModerna \u9032\u8ecd\u9ad4\u5167 CAR-T \u9818\u57df\uff0c\u6388\u4e88\u81ea\u9ad4"},"content":{"rendered":"\n<style>.wit-daily {\n  --bg:#0f0e0c;--bg2:#16140f;--fg:#e8e3d8;--dim:#8a8276;--mute:#5a5448;\n  --card:#1a1816;--card2:#221f1b;--bdr:#3a342e;--bdr2:#4a423a;\n  --acc:#c4b09a;--acc2:#d4a574;--acc3:#7a6e62;\n  --tw:#e07a6a;--us:#7ab3d4;\n  --up:#8fc78a;--dn:#d97070;--nu:#9a9282;\n  --warn:#d4a574;\n  --line-h:1.85;\n}\n.wit-daily * {margin:0;padding:0;box-sizing:border-box}\n.wit-daily {background:var(--bg)}\n.wit-daily {font-family:\"Noto Sans 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6px 0 6px 16px !important;\n  font-style: italic !important;\n  margin: 0 !important;\n  box-shadow: none !important;\n}\n.wit-daily .c-counter blockquote::before,\n.wit-daily blockquote::before,\n.wit-daily blockquote::after { content: none !important; }\n<\/style>\n<div class=\"wit-daily\">\n\n<main class=\"wrap\">\n<header class=\"hdr\">\n<div class=\"hdr-date\"><time datetime=\"2026-06-29\">2026 \u5e74 06 \u6708 29 \u65e5<\/time><\/div>\n<h1>\u751f\u91ab\u5927\u5065\u5eb7\u7522\u696d\u65e5\u5831<\/h1>\n<p class=\"hdr-sub\">\u5171\u6536\u9304 4 \u5247\u7522\u696d\u76f8\u95dc\u65b0\u805e \u00b7 2 \u5247\u7cbe\u9078\u6df1\u5ea6\u5206\u6790<\/p>\n<\/header>\n<section aria-labelledby=\"sec-featured\">\n<h2 class=\"lbl\" id=\"sec-featured\">\u7cbe\u9078\u6df1\u5ea6\u5206\u6790<\/h2>\n<article class=\"c\" itemscope=\"\" itemtype=\"https:\/\/schema.org\/NewsArticle\">\n<header class=\"c-hd\">\n<span class=\"c-cat\" style=\"--cc:#70AD47\">\u65b0\u8208\u7642\u6cd5<\/span>\n<span class=\"c-snt s-up\">\u25b2 \u504f\u591a<\/span>\n<\/header>\n<h3 class=\"c-t\" itemprop=\"headline\"><a href=\"https:\/\/www.fiercebiotech.com\/biotech\/moderna-enters-vivo-car-t-granting-autoimmune-asset-007-license-kill-pathogenic-cells\" rel=\"noopener nofollow\" target=\"_blank\">Moderna \u9032\u8ecd\u9ad4\u5167 CAR-T \u9818\u57df\uff0c\u6388\u4e88\u81ea\u9ad4\u514d\u75ab\u8cc7\u7522\u300c007\u300d\u6bba\u6ec5\u75c5\u7406\u7d30\u80de\u7684\u6388\u6b0a<\/a><\/h3>\n<div class=\"c-src\">\u4f86\u6e90\uff1a<span itemprop=\"publisher\">FierceBiotech<\/span> \u00b7 <time datetime=\"2026-06-29\" itemprop=\"datePublished\">2026-06-29<\/time><\/div>\n<div class=\"c-hype\"><span class=\"c-hype-lb\">\u7522\u696d\u91cd\u8981\u6027<\/span><span class=\"c-hype-dots\">\u25cf\u25cf\u25cf\u25cf\u25cb<\/span><span class=\"c-hype-tx\">4\/5 \u00b7 \u91cd\u5927\u8a0a\u865f<\/span><\/div>\n<div class=\"c-stocks\"><span class=\"stk stk-us\"><b>MRNA<\/b> Moderna <span class=\"chg chg-up\">\u25b212.59% $67.27<\/span><\/span><span class=\"stk stk-other\">Carisma Therapeutics <span class=\"chg chg-flat\">\u672a\u4e0a\u5e02<\/span><\/span><span class=\"stk stk-us\"><b>BMY<\/b> Bristol-Myers Squibb <span class=\"chg chg-up\">\u25b23.85% $57.52<\/span><\/span><span class=\"stk stk-us\"><b>NVS<\/b> Novartis <span class=\"chg chg-up\">\u25b20.19% $155.41<\/span><\/span><span class=\"stk stk-other\">Poseida Therapeutics <span class=\"chg chg-flat\">\u672a\u4e0a\u5e02<\/span><\/span><span class=\"stk stk-other\">Capstan Therapeutics <span class=\"chg chg-flat\">\u672a\u4e0a\u5e02<\/span><\/span><span class=\"stk stk-other\">\u514d\u75ab\u529f\u574a <span class=\"chg chg-flat\">\u672a\u4e0a\u5e02<\/span><\/span><\/div>\n<img decoding=\"async\" alt=\"Moderna \u9032\u8ecd\u9ad4\u5167 CAR-T \u9818\u57df\uff0c\u6388\u4e88\u81ea\u9ad4\u514d\u75ab\u8cc7\u7522\u300c007\u300d\u6bba\u6ec5\u75c5\u7406\u7d30\u80de\u7684\u6388\u6b0a\" class=\"lazyload c-img\" height=\"540\" loading=\"lazy\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271170%27%20height%3D%27540%27%20viewBox%3D%270%200%201170%20540%27%3E%3Crect%20width%3D%271170%27%20height%3D%27540%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/witology.com.tw\/wp-content\/uploads\/2026\/06\/featured_1-41.png\" width=\"1170\"\/>\n<section class=\"c-analysis\" itemprop=\"articleBody\">\n<div class=\"c-sec\">\n<h4>\u95dc\u9375\u4e8b\u4ef6<\/h4>\n<p>Moderna \u5ba3\u5e03\u900f\u904e mRNA \u5e73\u53f0\u5207\u5165\u9ad4\u5167\uff08in vivo\uff09CAR-T \u9818\u57df\uff0c\u5c07\u5176\u81ea\u9ad4\u514d\u75ab\u7ba1\u7dda\u8cc7\u7522\u4ee3\u865f\u300c007\u300d\u4ee5\u6388\u6b0a\u65b9\u5f0f\u8ce6\u4e88\u5176\u300c\u6bba\u6ec5\u75c5\u7406\u7d30\u80de\u300d\u7684\u529f\u80fd\uff0c\u6a19\u8a8c Moderna \u6b63\u5f0f\u5c07 mRNA \u6280\u8853\u5f9e\u764c\u75c7\u75ab\u82d7\u8207\u611f\u67d3\u75c7\u64f4\u5c55\u81f3\u81ea\u9ad4\u514d\u75ab\u7d30\u80de\u6cbb\u7642\u3002\u8207\u50b3\u7d71\u9ad4\u5916\uff08ex vivo\uff09CAR-T \u4e0d\u540c\uff0cin vivo CAR-T \u76f4\u63a5\u5728\u60a3\u8005\u9ad4\u5167\u91cd\u7de8\u7a0b\u514d\u75ab\u7d30\u80de\uff0c\u5927\u5e45\u964d\u4f4e\u88fd\u9020\u8907\u96dc\u5ea6\u8207\u6210\u672c\u3002\u6b64\u8209\u662f Moderna \u8fd1\u5e74\u591a\u89d2\u5316\u5e03\u5c40\u7684\u91cd\u8981\u4e00\u6b65\uff0c\u4e5f\u9a57\u8b49 mRNA \u905e\u9001\u5e73\u53f0\u5728\u7d30\u80de\u6cbb\u7642\u9818\u57df\u7684\u6280\u8853\u53ef\u884c\u6027\u3002<\/p>\n<\/div>\n<div class=\"c-sec\">\n<h4>\u95dc\u9375\u6578\u64da<\/h4>\n<p>\u50b3\u7d71 ex vivo CAR-T \u7642\u7a0b\u8cbb\u7528\u9ad8\u9054 30\u201345 \u842c\u7f8e\u5143\uff0c\u800c in vivo CAR-T \u7406\u8ad6\u4e0a\u53ef\u5c07\u6210\u672c\u964d\u4f4e 80% \u4ee5\u4e0a\uff1b\u5168\u7403 CAR-T \u5e02\u5834\u898f\u6a21 2023 \u5e74\u7d04 30 \u5104\u7f8e\u5143\uff0c\u9810\u8a08 2030 \u5e74\u8d85\u904e 100 \u5104\u7f8e\u5143\uff1b\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\u5168\u7403\u60a3\u8005\u903e 5 \u5104\u4eba\uff0c\u662f CAR-T \u6280\u8853\u62d3\u5c55\u5f8c\u6700\u5927\u7684\u6f5b\u5728\u53d7\u76ca\u5e02\u5834\uff1bModerna 2024 \u5e74 mRNA \u5e73\u53f0\u7814\u767c\u652f\u51fa\u8d85\u904e 45 \u5104\u7f8e\u5143\uff0c\u986f\u793a\u5176\u6301\u7e8c\u62bc\u6ce8\u975e\u75ab\u82d7\u9069\u61c9\u75c7\u3002<\/p>\n<\/div>\n<div class=\"c-sec c-wide\">\n<h4>\u5e02\u5834\u91cd\u8981\u6027<\/h4>\n<p>Moderna \u4ee5 mRNA \u5e73\u53f0\u5207\u5165 in vivo CAR-T \u81ea\u9ad4\u514d\u75ab\u9818\u57df\uff0c\u4ee3\u8868\u7d30\u80de\u6cbb\u7642\u5178\u7bc4\u6b63\u5f9e\u300c\u5de5\u5ee0\u88fd\u9020\u2192\u56de\u8f38\u300d\u8f49\u5411\u300c\u9ad4\u5167\u76f4\u63a5\u91cd\u7de8\u7a0b\u300d\uff0c\u82e5\u6280\u8853\u6210\u719f\u5c07\u985b\u8986\u73fe\u6709 CAR-T \u4f9b\u61c9\u93c8\u751f\u614b\u3002\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\uff08\u5982\u7d05\u6591\u6027\u72fc\u7621\u3001\u985e\u98a8\u6fd5\u95dc\u7bc0\u708e\uff09\u60a3\u8005\u57fa\u6578\u9060\u5927\u65bc\u8840\u6db2\u816b\u7624\uff0c\u4e00\u65e6 in vivo CAR-T \u9a57\u8b49\u7642\u6548\uff0c\u5e02\u5834\u5929\u82b1\u677f\u5c07\u6578\u500d\u65bc\u76ee\u524d\u816b\u7624\u9069\u61c9\u75c7\u3002\u5c0d\u53f0\u7063\u5ee0\u5546\u800c\u8a00\uff0c\u64c5\u9577\u8102\u8cea\u5948\u7c73\u7c92\u5b50\uff08LNP\uff09\u905e\u9001\u6750\u6599\u7684\u5ee0\u5546\uff08\u5982\u53f0\u7063\u8102\u8cea\u6280\u8853\u76f8\u95dc\u4f9b\u61c9\u5546\uff09\u53ca CDMO \u696d\u8005\u503c\u5f97\u95dc\u6ce8\u6f5b\u5728\u4f9b\u61c9\u93c8\u6a5f\u6703\u3002\u7136\u800c in vivo CAR-T \u5728\u81ea\u9ad4\u514d\u75ab\u9818\u57df\u5c1a\u7121\u5927\u898f\u6a21\u4eba\u9ad4\u81e8\u5e8a\u6578\u64da\uff0cModerna \u7684 mRNA \u5e73\u53f0\u80fd\u5426\u7cbe\u6e96\u9776\u5411\u75c5\u7406 B \u7d30\u80de\u6216\u6f3f\u7d30\u80de\u800c\u4e0d\u50b7\u53ca\u6b63\u5e38\u514d\u75ab\u7d30\u80de\uff0c\u4ecd\u662f\u6700\u5927\u7684\u6280\u8853\u8207\u5b89\u5168\u6027\u672a\u77e5\u6578\u3002<\/p>\n<\/div>\n<div class=\"c-sec c-wide c-counter\">\n<h4>\u26a0 \u53cd\u9762\u89c0\u9ede<\/h4>\n<blockquote>in vivo CAR-T \u6982\u5ff5\u96d6\u5438\u5f15\u4eba\uff0c\u4f46\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\u7684\u75c5\u7406\u7d30\u80de\u7570\u8cea\u6027\u9060\u9ad8\u65bc\u8840\u6db2\u816b\u7624\uff0c\u9776\u9ede\u9078\u64c7\u7a0d\u6709\u504f\u5dee\u5373\u53ef\u80fd\u5f15\u767c\u56b4\u91cd\u7684\u514d\u75ab\u98a8\u66b4\u6216\u812b\u9776\u6bd2\u6027\uff1b\u52a0\u4e0a Moderna \u5728\u7d30\u80de\u6cbb\u7642\u9818\u57df\u5e7e\u4e4e\u7121\u81e8\u5e8atrack record\uff0c\u300c007\u6388\u6b0a\u300d\u66f4\u591a\u50cf\u662f\u65e9\u671f\u6982\u5ff5\u9a57\u8b49\uff0c\u8ddd\u96e2\u771f\u6b63\u7684\u81e8\u5e8a\u7a81\u7834\u53ef\u80fd\u4ecd\u9700 5\u20138 \u5e74\uff0c\u5e02\u5834\u4e0d\u5b9c\u904e\u5ea6\u5b9a\u50f9\u3002<\/blockquote>\n<\/div>\n<div class=\"c-sec c-wide c-watch\">\n<h4>\ud83d\udccd \u63a5\u4e0b\u4f86\u89c0\u5bdf<\/h4>\n<div class=\"c-watch-grid\">\n<div class=\"c-watch-col\"><div class=\"c-watch-h c-w-short\">\ud83d\udd25 \u77ed\u671f\u50ac\u5316\u5291<span>1-3 \u500b\u6708<\/span><\/div><ul><li>Moderna \u516c\u5e03\u300c007\u300d\u8cc7\u7522\u7684\u5177\u9ad4\u9776\u9ede\u8207 IND\uff08\u81e8\u5e8a\u8a66\u9a57\u7533\u8acb\uff09\u6642\u7a0b<\/li><li>\u7af6\u722d\u5c0d\u624b Capstan Therapeutics\u3001Poseida \u7b49 in vivo CAR-T \u516c\u53f8\u662f\u5426\u8ddf\u9032\u81ea\u9ad4\u514d\u75ab\u9069\u61c9\u75c7\u5e03\u5c40<\/li><\/ul><\/div>\n<div class=\"c-watch-col\"><div class=\"c-watch-h c-w-mid\">\ud83d\udc41 \u4e2d\u671f\u89c0\u5bdf<span>3-12 \u500b\u6708<\/span><\/div><ul><li>Moderna mRNA-CAR-T \u5e73\u53f0\u9996\u6279\u81ea\u9ad4\u514d\u75ab\u60a3\u8005\u7684 Phase I \u5b89\u5168\u6027\u8207\u521d\u6b65\u7642\u6548\u6578\u64da<\/li><li>\u5927\u578b\u85e5\u5ee0\uff08BMS\u3001Novartis \u7b49\u73fe\u6709 CAR-T \u73a9\u5bb6\uff09\u662f\u5426\u900f\u904e\u4f75\u8cfc\u6216\u6388\u6b0a\u56de\u61c9 in vivo \u7af6\u722d\u58d3\u529b<\/li><\/ul><\/div>\n<div class=\"c-watch-col\"><div class=\"c-watch-h c-w-long\">\ud83c\udfaf \u9577\u671f\u8b8a\u6578<span>1 \u5e74\u4ee5\u4e0a<\/span><\/div><ul><li>in vivo CAR-T \u662f\u5426\u80fd\u5efa\u7acb\u76e3\u7ba1\u6a19\u6e96\uff08FDA \u5c0d mRNA \u9a45\u52d5\u7d30\u80de\u91cd\u7de8\u7a0b\u7684\u5be9\u67e5\u6846\u67b6\uff09<\/li><li>LNP \u905e\u9001\u6280\u8853\u7684\u7d44\u7e54\u7279\u7570\u6027\u80fd\u5426\u7a81\u7834\uff0c\u6c7a\u5b9a in vivo CAR-T \u898f\u6a21\u5316\u5546\u696d\u61c9\u7528\u7684\u5929\u82b1\u677f<\/li><\/ul><\/div>\n<\/div>\n<\/div>\n<div class=\"c-sec c-wide c-faqs\">\n<h4>\u2753 \u5e38\u898b\u554f\u984c<\/h4>\n<details class=\"c-faq-item\"><summary>in vivo CAR-T \u8ddf\u50b3\u7d71 CAR-T \u6709\u4ec0\u9ebc\u4e0d\u540c\uff1f\u70ba\u4ec0\u9ebc Moderna \u8981\u8d70\u9019\u689d\u8def\uff1f<\/summary><p>\u50b3\u7d71 CAR-T \u9700\u62bd\u53d6\u60a3\u8005\u514d\u75ab\u7d30\u80de\u5230\u9ad4\u5916\u6539\u9020\u5f8c\u518d\u56de\u8f38\uff0c\u88fd\u7a0b\u8017\u6642\u4e14\u6602\u8cb4\uff1bin vivo CAR-T \u5247\u900f\u904e mRNA \u6216\u75c5\u6bd2\u8f09\u9ad4\u76f4\u63a5\u5728\u60a3\u8005\u9ad4\u5167\u5c07 T \u7d30\u80de\u91cd\u7de8\u7a0b\uff0c\u7406\u8ad6\u4e0a\u53ef\u5927\u5e45\u964d\u4f4e\u6210\u672c\u4e26\u7e2e\u77ed\u6cbb\u7642\u7b49\u5f85\u6642\u9593\uff0c\u9019\u6b63\u662f\u64c1\u6709 mRNA \u905e\u9001\u5e73\u53f0\u7684 Moderna \u7684\u6838\u5fc3\u7af6\u722d\u512a\u52e2\u6240\u5728\u3002<\/p><\/details><details class=\"c-faq-item\"><summary>\u9019\u500b\u300c007\u300d\u8cc7\u7522\u662f\u91dd\u5c0d\u4ec0\u9ebc\u75be\u75c5\uff1f\u76ee\u524d\u9032\u5c55\u5230\u54ea\u500b\u968e\u6bb5\uff1f<\/summary><p>\u6839\u64da\u5831\u5c0e\uff0c\u300c007\u300d\u5b9a\u4f4d\u65bc\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\uff08\u5982\u7d05\u6591\u6027\u72fc\u7621\u6216 B \u7d30\u80de\u4ecb\u5c0e\u7684\u81ea\u9ad4\u514d\u75ab\u75c5\uff09\uff0c\u76ee\u6a19\u662f\u6bba\u6ec5\u9020\u6210\u514d\u75ab\u5931\u8abf\u7684\u75c5\u7406\u7d30\u80de\uff1b\u76ee\u524d\u4ecd\u8655\u65bc\u65e9\u671f\u7814\u7a76\u6216\u6388\u6b0a\u5408\u4f5c\u968e\u6bb5\uff0c\u5c1a\u672a\u9032\u5165\u4eba\u9ad4\u81e8\u5e8a\u8a66\u9a57\uff0c\u8ddd\u96e2\u4e0a\u5e02\u4ecd\u6709\u76f8\u7576\u8ddd\u96e2\u3002<\/p><\/details><details class=\"c-faq-item\"><summary>Moderna \u505a CAR-T \u5c0d\u73fe\u6709\u7684 CAR-T \u5ee0\u5546\uff08\u5982 Novartis\u3001BMS\uff09\u6709\u4ec0\u9ebc\u5f71\u97ff\uff1f<\/summary><p>\u77ed\u671f\u885d\u64ca\u6709\u9650\uff0c\u56e0 Moderna \u4ecd\u5728\u65e9\u671f\u968e\u6bb5\uff1b\u4f46\u9577\u671f\u4f86\u770b\uff0c\u82e5 in vivo \u8def\u7dda\u88ab\u9a57\u8b49\uff0c\u5c07\u76f4\u63a5\u5a01\u8105\u4f9d\u8cf4\u8907\u96dc\u9ad4\u5916\u88fd\u9020\u6d41\u7a0b\u7684\u73fe\u6709\u5ee0\u5546\uff0c\u8feb\u4f7f Novartis\uff08Kymriah\uff09\u8207 BMS\uff08Breyanzi\uff09\u52a0\u901f\u5e03\u5c40 in vivo \u6280\u8853\u6216\u900f\u904e\u4f75\u8cfc\u9632\u79a6\u3002<\/p><\/details>\n<\/div>\n<\/section>\n<footer class=\"c-ft\"><a href=\"https:\/\/www.fiercebiotech.com\/biotech\/moderna-enters-vivo-car-t-granting-autoimmune-asset-007-license-kill-pathogenic-cells\" rel=\"noopener nofollow\" target=\"_blank\">\u95b1\u8b80\u539f\u6587 \u2192<\/a><\/footer>\n<\/article>\n<article class=\"c\" itemscope=\"\" itemtype=\"https:\/\/schema.org\/NewsArticle\">\n<header class=\"c-hd\">\n<span class=\"c-cat\" style=\"--cc:#70AD47\">\u65b0\u8208\u7642\u6cd5<\/span>\n<span class=\"c-snt s-up\">\u25b2 \u504f\u591a<\/span>\n<\/header>\n<h3 class=\"c-t\" itemprop=\"headline\"><a href=\"https:\/\/www.fiercebiotech.com\/biotech\/epicrispr-gene-silencer-becomes-first-enhance-muscle-form-muscular-dystrophy\" rel=\"noopener nofollow\" target=\"_blank\">Epicrispr \u57fa\u56e0\u975c\u9ed8\u7642\u6cd5\u6210\u70ba\u9996\u6b3e\u6539\u5584\u808c\u8089\u840e\u7e2e\u75c7\u808c\u8089\u91cf\u7684\u85e5\u7269\uff0c\u751f\u6280\u516c\u53f8\u5ba3\u5e03<\/a><\/h3>\n<div class=\"c-src\">\u4f86\u6e90\uff1a<span itemprop=\"publisher\">FierceBiotech<\/span> \u00b7 <time datetime=\"2026-06-29\" itemprop=\"datePublished\">2026-06-29<\/time><\/div>\n<div class=\"c-hype\"><span class=\"c-hype-lb\">\u7522\u696d\u91cd\u8981\u6027<\/span><span class=\"c-hype-dots\">\u25cf\u25cf\u25cf\u25cb\u25cb<\/span><span class=\"c-hype-tx\">3\/5 \u00b7 \u503c\u5f97\u95dc\u6ce8<\/span><\/div>\n<div class=\"c-stocks\"><span class=\"stk stk-other\">Epicrispr Biotechnologies <span class=\"chg chg-flat\">\u672a\u4e0a\u5e02<\/span><\/span><span class=\"stk stk-us\"><b>SRPT<\/b> Sarepta Therapeutics <span class=\"chg chg-up\">\u25b25.18% $16.85<\/span><\/span><span class=\"stk stk-us\"><b>SLDB<\/b> Solid Biosciences <span class=\"chg chg-up\">\u25b24.85% $9.29<\/span><\/span><span class=\"stk stk-us\"><b>EDIT<\/b> Editas Medicine <span class=\"chg chg-up\">\u25b24.01% $2.85<\/span><\/span><span class=\"stk stk-us\"><b>BEAM<\/b> Beam Therapeutics <span class=\"chg chg-up\">\u25b22.59% $34.81<\/span><\/span><span class=\"stk stk-us\"><b>WVE<\/b> Wave Life Sciences <span class=\"chg chg-up\">\u25b21.39% $5.83<\/span><\/span><span class=\"stk stk-other\"><b>ROG<\/b> Roche <span class=\"chg chg-down\">\u25bc3.93% $160.53<\/span><\/span><\/div>\n<img decoding=\"async\" alt=\"Epicrispr \u57fa\u56e0\u975c\u9ed8\u7642\u6cd5\u6210\u70ba\u9996\u6b3e\u6539\u5584\u808c\u8089\u840e\u7e2e\u75c7\u808c\u8089\u91cf\u7684\u85e5\u7269\uff0c\u751f\u6280\u516c\u53f8\u5ba3\u5e03\" class=\"lazyload c-img\" height=\"540\" loading=\"lazy\" src=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271170%27%20height%3D%27540%27%20viewBox%3D%270%200%201170%20540%27%3E%3Crect%20width%3D%271170%27%20height%3D%27540%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-orig-src=\"https:\/\/witology.com.tw\/wp-content\/uploads\/2026\/06\/featured_2-42.png\" width=\"1170\"\/>\n<section class=\"c-analysis\" itemprop=\"articleBody\">\n<div class=\"c-sec\">\n<h4>\u95dc\u9375\u4e8b\u4ef6<\/h4>\n<p>\u751f\u6280\u516c\u53f8 Epicrispr Biotechnologies \u5ba3\u5e03\u5176\u57fa\u56e0\u975c\u9ed8\uff08gene silencing\uff09\u7642\u6cd5\u5728\u67d0\u4e00\u985e\u578b\u808c\u8089\u840e\u7e2e\u75c7\u7684\u81e8\u5e8a\u8a66\u9a57\u4e2d\uff0c\u9996\u6b21\u8b49\u660e\u80fd\u5be6\u969b\u589e\u52a0\u60a3\u8005\u808c\u8089\u91cf\uff0c\u6210\u70ba\u540c\u985e\u75be\u75c5\u4e2d\u9996\u6b3e\u9054\u5230\u6b64\u91cc\u7a0b\u7891\u7684\u85e5\u7269\u3002\u8a72\u6280\u8853\u904b\u7528\u8868\u89c0\u907a\u50b3\uff08epigenetic\uff09\u8abf\u63a7\u6a5f\u5236\u975c\u9ed8\u7279\u5b9a\u81f4\u75c5\u57fa\u56e0\uff0c\u800c\u975e\u76f4\u63a5\u5207\u5272 DNA\uff0c\u7406\u8ad6\u4e0a\u5b89\u5168\u6027\u512a\u65bc\u50b3\u7d71 CRISPR \u57fa\u56e0\u7de8\u8f2f\u3002\u6b64\u7d50\u679c\u82e5\u7372\u5927\u578b\u81e8\u5e8a\u9a57\u8b49\uff0c\u5c07\u958b\u555f\u8868\u89c0\u907a\u50b3\u57fa\u56e0\u975c\u9ed8\u5728\u795e\u7d93\u808c\u8089\u75be\u75c5\u7684\u65b0\u6cbb\u7642\u5178\u7bc4\u3002<\/p>\n<\/div>\n<div class=\"c-sec\">\n<h4>\u95dc\u9375\u6578\u64da<\/h4>\n<p>\u808c\u8089\u840e\u7e2e\u75c7\uff08Muscular Dystrophy\uff09\u5168\u7403\u60a3\u8005\u4f30\u8a08\u8d85\u904e 25 \u842c\u4eba\uff0c\u76ee\u524d\u4e3b\u8981\u6cbb\u7642\u9078\u9805\u6709\u9650\u4e14\u7642\u6548\u4e0d\u8db3\uff1bSarepta \u7684 Duchenne \u808c\u8089\u840e\u7e2e\u75c7\u57fa\u56e0\u7642\u6cd5 Elevidys \u4e0a\u5e02\u5b9a\u50f9\u7d04 320 \u842c\u7f8e\u5143\/\u5291\uff0c\u986f\u793a\u7f55\u898b\u795e\u7d93\u808c\u8089\u75be\u75c5\u7684\u5b9a\u50f9\u7a7a\u9593\u6975\u5927\uff1b\u8868\u89c0\u907a\u50b3\u57fa\u56e0\u975c\u9ed8\u5168\u7403\u5e02\u5834\u9810\u4f30 2030 \u5e74\u5c07\u9054 15\u201320 \u5104\u7f8e\u5143\uff1bEpicrispr \u76ee\u524d\u70ba\u79c1\u4eba\u516c\u53f8\uff0c\u5177\u9ad4\u878d\u8cc7\u8f2a\u6b21\u672a\u516c\u958b\uff0c\u4f46\u540c\u985e\u57fa\u56e0\u975c\u9ed8\u6280\u8853\u516c\u53f8\u8fd1\u5e74\u7372\u5f97\u7684 A \u8f2a\u878d\u8cc7\u5e73\u5747\u903e 1 \u5104\u7f8e\u5143\u3002<\/p>\n<\/div>\n<div class=\"c-sec c-wide\">\n<h4>\u5e02\u5834\u91cd\u8981\u6027<\/h4>\n<p>Epicrispr \u7684\u81e8\u5e8a\u6578\u64da\u6a19\u8a8c\u8868\u89c0\u907a\u50b3\u57fa\u56e0\u975c\u9ed8\uff08epigenetic silencing\uff09\u9996\u6b21\u5728\u795e\u7d93\u808c\u8089\u75be\u75c5\u4e2d\u5c55\u73fe\u300c\u589e\u808c\u300d\u7684\u529f\u80fd\u6027\u6539\u5584\uff0c\u800c\u975e\u50c5\u6b62\u65bc\u751f\u7269\u6a19\u8a18\u8b8a\u5316\uff0c\u662f\u57fa\u56e0\u6cbb\u7642\u9818\u57df\u7684\u91cd\u8981\u6982\u5ff5\u9a57\u8b49\u3002\u76f8\u8f03\u65bc\u76f4\u63a5 DNA \u5207\u5272\u7684 CRISPR\uff0c\u8868\u89c0\u907a\u50b3\u8abf\u63a7\u5177\u6709\u53ef\u9006\u6027\u8207\u8f03\u4f4e\u812b\u9776\u98a8\u96aa\uff0c\u82e5\u5b89\u5168\u6027\u6578\u64da\u6301\u7e8c\u826f\u597d\uff0c\u6709\u671b\u52a0\u901f\u76e3\u7ba1\u6a5f\u69cb\u5c0d\u6b64\u985e\u6280\u8853\u7684\u63a5\u53d7\u5ea6\u3002\u5c0d\u6574\u9ad4\u57fa\u56e0\u6cbb\u7642\u7522\u696d\u800c\u8a00\uff0c\u6b64\u7a81\u7834\u53ef\u80fd\u5438\u5f15\u66f4\u591a\u8cc7\u91d1\u6d41\u5165\u8868\u89c0\u907a\u50b3\u5e73\u53f0\u516c\u53f8\uff0c\u4e26\u5c0d Sarepta\u3001Solid Biosciences \u7b49\u73fe\u6709\u808c\u8089\u840e\u7e2e\u75c7\u5ee0\u5546\u5f62\u6210\u7af6\u722d\u58d3\u529b\u3002\u53f0\u7063\u57fa\u56e0\u6cbb\u7642 CDMO \u53ca AAV \u8f09\u9ad4\u88fd\u9020\u5ee0\u5546\uff08\u5982\u4e2d\u88d5\u65b0\u85e5\u3001\u535a\u665f\u751f\u91ab\u7b49\uff09\u53ef\u95dc\u6ce8\u6b64\u6280\u8853\u8def\u7dda\u7684\u4ee3\u5de5\u9700\u6c42\u6f5b\u529b\u3002<\/p>\n<\/div>\n<div class=\"c-sec c-wide c-counter\">\n<h4>\u26a0 \u53cd\u9762\u89c0\u9ede<\/h4>\n<blockquote>\u300c\u9996\u6b3e\u300d\u7684\u5ba3\u7a31\u4f86\u81ea\u516c\u53f8\u81ea\u8eab\u8072\u660e\u800c\u975e\u540c\u5115\u5be9\u67e5\u767c\u8868\uff0c\u6a23\u672c\u6578\u8207\u8ffd\u8e64\u6642\u9593\u6975\u53ef\u80fd\u6709\u9650\uff0c\u81e8\u5e8a\u610f\u7fa9\u9700\u8b39\u614e\u89e3\u8b80\uff1b\u808c\u8089\u840e\u7e2e\u75c7\u7a2e\u985e\u7e41\u591a\uff08Duchenne\u3001Becker\u3001\u80a2\u5e36\u578b\u7b49\uff09\uff0c\u6b64\u8a66\u9a57\u91dd\u5c0d\u7684\u7279\u5b9a\u4e9e\u578b\u82e5\u60a3\u8005\u57fa\u6578\u6975\u5c0f\uff0c\u5546\u696d\u5316\u898f\u6a21\u6050\u76f8\u7576\u53d7\u9650\uff0c\u4e14\u8868\u89c0\u907a\u50b3\u975c\u9ed8\u7684\u7642\u6548\u6301\u4e45\u6027\u8207\u7d66\u85e5\u983b\u7387\u4ecd\u662f\u672a\u89e3\u96e3\u984c\u3002<\/blockquote>\n<\/div>\n<div class=\"c-sec c-wide c-watch\">\n<h4>\ud83d\udccd \u63a5\u4e0b\u4f86\u89c0\u5bdf<\/h4>\n<div class=\"c-watch-grid\">\n<div class=\"c-watch-col\"><div class=\"c-watch-h c-w-short\">\ud83d\udd25 \u77ed\u671f\u50ac\u5316\u5291<span>1-3 \u500b\u6708<\/span><\/div><ul><li>Epicrispr \u516c\u5e03\u5b8c\u6574\u81e8\u5e8a\u8a66\u9a57\u6578\u64da\uff08\u60a3\u8005\u4eba\u6578\u3001\u808c\u8089\u91cf\u589e\u5e45\u5177\u9ad4\u6578\u503c\u3001\u8ffd\u8e64\u9031\u671f\uff09<\/li><li>\u540c\u5115\u5be9\u67e5\u671f\u520a\u6295\u7a3f\u6216\u91cd\u8981\u91ab\u5b78\u6703\u8b70\uff08\u5982 MDA \u5927\u6703\uff09\u53e3\u982d\u5831\u544a\u6642\u7a0b<\/li><\/ul><\/div>\n<div class=\"c-watch-col\"><div class=\"c-watch-h c-w-mid\">\ud83d\udc41 \u4e2d\u671f\u89c0\u5bdf<span>3-12 \u500b\u6708<\/span><\/div><ul><li>Epicrispr \u555f\u52d5\u66f4\u5927\u898f\u6a21 Phase II \u8a66\u9a57\u53ca FDA \u6e9d\u901a\u53d6\u5f97\u7a81\u7834\u6027\u7642\u6cd5\u8a8d\u5b9a\u7684\u53ef\u80fd\u6027<\/li><li>\u5927\u578b\u85e5\u5ee0\uff08Roche\u3001Biogen\u3001Sarepta\uff09\u662f\u5426\u4e3b\u52d5\u63a5\u89f8\u4f75\u8cfc\u6216\u6388\u6b0a\u5408\u4f5c<\/li><\/ul><\/div>\n<div class=\"c-watch-col\"><div class=\"c-watch-h c-w-long\">\ud83c\udfaf \u9577\u671f\u8b8a\u6578<span>1 \u5e74\u4ee5\u4e0a<\/span><\/div><ul><li>\u8868\u89c0\u907a\u50b3\u57fa\u56e0\u975c\u9ed8\u6280\u8853\u80fd\u5426\u5f9e\u7f55\u898b\u808c\u8089\u75be\u75c5\u62d3\u5c55\u81f3\u66f4\u5927\u9069\u61c9\u75c7\uff08\u5982 ALS\u3001\u5fc3\u808c\u75c5\uff09<\/li><li>\u57fa\u56e0\u975c\u9ed8\u7642\u6cd5\u7684\u7d66\u85e5\u6a21\u5f0f\uff08\u4e00\u6b21\u6027 vs. \u91cd\u8907\u7d66\u85e5\uff09\u5c0d\u5b9a\u50f9\u7b56\u7565\u8207\u91ab\u7642\u652f\u4ed8\u9ad4\u7cfb\u7684\u7d50\u69cb\u6027\u5f71\u97ff<\/li><\/ul><\/div>\n<\/div>\n<\/div>\n<div class=\"c-sec c-wide c-faqs\">\n<h4>\u2753 \u5e38\u898b\u554f\u984c<\/h4>\n<details class=\"c-faq-item\"><summary>\u300c\u57fa\u56e0\u975c\u9ed8\u300d\u8ddf\u4e00\u822c\u7684 CRISPR \u57fa\u56e0\u7de8\u8f2f\u6709\u4ec0\u9ebc\u5dee\u5225\uff1f\u9019\u500b\u7642\u6cd5\u662f\u600e\u9ebc\u904b\u4f5c\u7684\uff1f<\/summary><p>CRISPR \u57fa\u56e0\u7de8\u8f2f\u6703\u76f4\u63a5\u5207\u65b7\u4e26\u4fee\u6539 DNA \u5e8f\u5217\uff0c\u5c6c\u65bc\u6c38\u4e45\u6027\u6539\u8b8a\uff1b\u57fa\u56e0\u975c\u9ed8\uff08gene silencing\uff09\u5247\u662f\u900f\u904e\u8868\u89c0\u907a\u50b3\u6a5f\u5236\u300c\u95dc\u6389\u300d\u7279\u5b9a\u57fa\u56e0\u7684\u8868\u73fe\uff0c\u4e0d\u6539\u8b8a DNA \u672c\u8eab\uff0c\u7406\u8ad6\u4e0a\u66f4\u53ef\u9006\u3001\u812b\u9776\u98a8\u96aa\u66f4\u4f4e\uff0cEpicrispr \u7684\u6280\u8853\u5373\u5c6c\u6b64\u985e\u3002<\/p><\/details><details class=\"c-faq-item\"><summary>\u9019\u500b\u7642\u6cd5\u662f\u91dd\u5c0d\u54ea\u4e00\u7a2e\u808c\u8089\u840e\u7e2e\u75c7\uff1f\u8ddf\u6700\u5e38\u898b\u7684 Duchenne \u808c\u8089\u840e\u7e2e\u75c7\u6709\u95dc\u55ce\uff1f<\/summary><p>\u6839\u64da\u5831\u5c0e\uff0cEpicrispr \u7684\u7642\u6cd5\u91dd\u5c0d\u7279\u5b9a\u985e\u578b\u7684\u808c\u8089\u840e\u7e2e\u75c7\uff08\u5177\u9ad4\u4e9e\u578b\u5f85\u516c\u53f8\u6b63\u5f0f\u516c\u5e03\uff09\uff0c\u662f\u5426\u6db5\u84cb\u6700\u5e38\u898b\u7684 Duchenne \u578b\u5c1a\u672a\u78ba\u8a8d\uff1bDuchenne \u76ee\u524d\u5df2\u6709 Sarepta \u7684 Elevidys \u57fa\u56e0\u7642\u6cd5\u7372\u6279\uff0cEpicrispr \u82e5\u7784\u6e96\u4e0d\u540c\u4e9e\u578b\u5247\u53ef\u586b\u88dc\u73fe\u6709\u6cbb\u7642\u7a7a\u767d\u3002<\/p><\/details><details class=\"c-faq-item\"><summary>\u9019\u500b\u6d88\u606f\u5c0d\u76ee\u524d\u6295\u8cc7\u808c\u8089\u840e\u7e2e\u75c7\u7684\u85e5\u5ee0\u80a1\u7968\u6709\u4ec0\u9ebc\u5f71\u97ff\uff1f<\/summary><p>\u77ed\u671f\u5167 Sarepta\uff08SRPT\uff09\u7b49\u73fe\u6709\u5ee0\u5546\u53ef\u80fd\u9762\u81e8\u7af6\u722d\u7591\u616e\u800c\u627f\u58d3\uff0c\u4f46 Epicrispr \u4ecd\u662f\u79c1\u4eba\u516c\u53f8\u4e14\u6578\u64da\u521d\u6b65\uff0c\u5be6\u969b\u5546\u696d\u5316\u5a01\u8105\u81f3\u5c11\u5728 5 \u5e74\u4ee5\u4e0a\uff1b\u5c0d\u6574\u9ad4\u57fa\u56e0\u6cbb\u7642\u677f\u584a\u5247\u5c6c\u6b63\u9762\u50ac\u5316\u5291\uff0c\u6709\u52a9\u63d0\u632f Beam Therapeutics\u3001Editas Medicine \u7b49\u8868\u89c0\u907a\u50b3\/\u57fa\u56e0\u7de8\u8f2f\u6982\u5ff5\u80a1\u7684\u5e02\u5834\u60c5\u7dd2\u3002<\/p><\/details>\n<\/div>\n<\/section>\n<footer class=\"c-ft\"><a href=\"https:\/\/www.fiercebiotech.com\/biotech\/epicrispr-gene-silencer-becomes-first-enhance-muscle-form-muscular-dystrophy\" rel=\"noopener nofollow\" target=\"_blank\">\u95b1\u8b80\u539f\u6587 \u2192<\/a><\/footer>\n<\/article>\n<\/section>\n<section aria-labelledby=\"sec-briefs\">\n<h2 class=\"lbl\" id=\"sec-briefs\">\u4eca\u65e5\u5feb\u8a0a<\/h2>\n<ul class=\"briefs\" style=\"list-style:none\">\n<li class=\"b-item\">\n<span class=\"b-dot\" style=\"background:#4472C4\"><\/span>\n<div><a class=\"b-link\" href=\"https:\/\/news.google.com\/rss\/articles\/CBMitwFBVV95cUxOU0paWnlfcjh6Q3hnMk5ETkI0M001TmtuSjl0M0hmaVo2Y2VRcTFJVDhfMW00ZGJnVlJfb01mRWNxU0FwSHVEa2JIQ3pfZk5wcWdHR21BUGNMeUZaSFpNQ0tkRFk3cGNibVNMTEEzTnpHaVRXcWZJbkRvX00wQ0t1MEFfWV9HREFNSW44Z0M0TDAxelQ0WUQyb21hYW9vN1VjN28teFFhcVdHVmY3RDdyV05OV2tWWGc?oc=5\" rel=\"noopener nofollow\" target=\"_blank\">IPO Debut | &#8220;Nephrology-focused biopharmaceutical company&#8221; LYRA PHARMA-B surged over 85% on its first trading day, yielding a HK$1,940 profit per lot. &#8211; \u5bcc\u9014\u725b\u725b<\/a>\n<span class=\"b-meta\">\u85e5\u7269 \u00b7 Google News &#8211; biopharmaceutical<\/span><\/div>\n<\/li>\n<\/ul>\n<\/section>\n<section aria-labelledby=\"sec-stats\" class=\"stats\" style=\"margin-top:48px\">\n<h2 class=\"lbl\" id=\"sec-stats\" style=\"font-size:16px;border-bottom-width:1px\">\u5206\u985e\u7d71\u8a08<\/h2>\n<div class=\"st\"><div class=\"st-bar\" style=\"width:50.0%;background:#4472C4\"><\/div><span class=\"st-lb\">\u85e5\u7269<\/span><span class=\"st-ct\">2<\/span><\/div><div class=\"st\"><div class=\"st-bar\" style=\"width:50.0%;background:#70AD47\"><\/div><span class=\"st-lb\">\u65b0\u8208\u7642\u6cd5<\/span><span class=\"st-ct\">2<\/span><\/div>\n<\/section>\n<!-- footer \u5df2\u79fb\u9664(v2.14.0) -->\n<\/main>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>2026 \u5e74 06 \u6708 29 \u65e5 \u751f\u91ab\u5927\u5065\u5eb7\u7522\u696d\u65e5\u5831 \u5171\u6536\u9304 4 \u5247\u7522\u696d\u76f8\u95dc\u65b0\u805e \u00b7 2 \u5247\u7cbe\u9078\u6df1\u5ea6\u5206\u6790 \u7cbe\u9078 [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":7356,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"rank_math_title":"\u751f\u91ab\u5927\u5065\u5eb7\u7522\u696d\u65e5\u5831 2026-06-29\uff5cModerna \u9032\u8ecd\u9ad4\u5167 CAR-T \u9818\u57df\uff0c\u6388\u4e88\u81ea\u9ad4","rank_math_description":"2026 \u5e74 06 \u6708 29 \u65e5 \u751f\u91ab\u5927\u5065\u5eb7\u7522\u696d\u65e5\u5831\uff1aModerna \u9032\u8ecd\u9ad4\u5167 CAR-T \u9818\u57df\uff0c\u6388\u4e88\u81ea\u9ad4\u514d\u75ab\u8cc7\u7522\u300c007\u300d\u3001Epicrispr 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\"CRISPR \u57fa\u56e0\u7de8\u8f2f\u6703\u76f4\u63a5\u5207\u65b7\u4e26\u4fee\u6539 DNA \u5e8f\u5217\uff0c\u5c6c\u65bc\u6c38\u4e45\u6027\u6539\u8b8a\uff1b\u57fa\u56e0\u975c\u9ed8\uff08gene silencing\uff09\u5247\u662f\u900f\u904e\u8868\u89c0\u907a\u50b3\u6a5f\u5236\u300c\u95dc\u6389\u300d\u7279\u5b9a\u57fa\u56e0\u7684\u8868\u73fe\uff0c\u4e0d\u6539\u8b8a DNA \u672c\u8eab\uff0c\u7406\u8ad6\u4e0a\u66f4\u53ef\u9006\u3001\u812b\u9776\u98a8\u96aa\u66f4\u4f4e\uff0cEpicrispr \u7684\u6280\u8853\u5373\u5c6c\u6b64\u985e\u3002\"\n        }\n      },\n      {\n        \"@type\": \"Question\",\n        \"name\": \"\u9019\u500b\u7642\u6cd5\u662f\u91dd\u5c0d\u54ea\u4e00\u7a2e\u808c\u8089\u840e\u7e2e\u75c7\uff1f\u8ddf\u6700\u5e38\u898b\u7684 Duchenne \u808c\u8089\u840e\u7e2e\u75c7\u6709\u95dc\u55ce\uff1f\",\n        \"acceptedAnswer\": {\n          \"@type\": \"Answer\",\n          \"text\": \"\u6839\u64da\u5831\u5c0e\uff0cEpicrispr 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\u4ecd\u662f\u79c1\u4eba\u516c\u53f8\u4e14\u6578\u64da\u521d\u6b65\uff0c\u5be6\u969b\u5546\u696d\u5316\u5a01\u8105\u81f3\u5c11\u5728 5 \u5e74\u4ee5\u4e0a\uff1b\u5c0d\u6574\u9ad4\u57fa\u56e0\u6cbb\u7642\u677f\u584a\u5247\u5c6c\u6b63\u9762\u50ac\u5316\u5291\uff0c\u6709\u52a9\u63d0\u632f Beam Therapeutics\u3001Editas Medicine \u7b49\u8868\u89c0\u907a\u50b3\/\u57fa\u56e0\u7de8\u8f2f\u6982\u5ff5\u80a1\u7684\u5e02\u5834\u60c5\u7dd2\u3002\"\n        }\n      }\n    ]\n  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